Stent Thrombosis and Bleeding Complications After Implantation of Sirolimus-Eluting Coronary Stents in an Unselected Worldwide Population: A Report From the e-SELECT (Multi-Center Post-Market Surveillance) Registry
Identifieur interne : 006706 ( Main/Exploration ); précédent : 006705; suivant : 006707Stent Thrombosis and Bleeding Complications After Implantation of Sirolimus-Eluting Coronary Stents in an Unselected Worldwide Population: A Report From the e-SELECT (Multi-Center Post-Market Surveillance) Registry
Auteurs : Philip Urban [Suisse] ; Alexandre Abizaid [Brésil] ; Adrian Banning [Royaume-Uni] ; Antonio L. Bartorelli [Italie] ; Ana Cebrian Baux [Belgique] ; Vladimir Dzavik [Canada] ; Stephen Ellis [États-Unis] ; Runlin Gao [République populaire de Chine] ; David Holmes [États-Unis] ; MYUNG HO JEONG [Corée du Sud] ; Victor Legrand [Belgique] ; Franz-Josef Neumann [Allemagne] ; Maria Nyakern [Belgique] ; Christian Spaulding [France] ; Stephen Worthley [Australie]Source :
- Journal of the American College of Cardiology [ 0735-1097 ] ; 2011.
Descripteurs français
- Pascal (Inist)
- Wicri :
- geographic : Région Centre.
- topic : Marché, Antibiotique.
English descriptors
- KwdEn :
Abstract
Objectives The aim of this study was to ascertain the 1-year incidence of stent thrombosis (ST) and major bleeding (MB) in a large, unselected population treated with sirolimus-eluting stents (SES). Background Stent thrombosis and MB are major potential complications of drug-eluting stent implantation. Their relative incidence and predisposing factors among large populations treated worldwide are unclear. Methods The SES were implanted in 15,147 patients who were entered in a multinational registry. We analyzed the incidence of: 1) definite and probable ST as defined by the Academic Research Consortium; and 2) MB, with the STEEPLE (Safety and efficacy of Enoxaparin in PCI) definition, together with their relation to dual antiplatelet therapy (DAPT) and to 1-year clinical outcomes. Results The mean age of the sample was 62 ± 11 years, 30.4% were diabetic, 10% had a Charlson comorbidity index ≥3, and 44% presented with acute coronary syndrome or myocardial infarction. At 1 year, the reported compli- ance with DAPT as recommended by the European Society of Cardiology guidelines was 86.3%. Adverse event rates were: ST 1.0%, MB 1.0%, mortality 1.7%, myocardial infarction 1.9%, and target lesion revascularization 2.3%. Multivariate analysis identified 9 correlates of ST and 4 correlates of MB. Advanced age and a high Charlson index were associated with an increased risk of both ST and MB. After ST, the 7-day and 1-year all-cause mortality was 30% and 35%, respectively, versus 1.5% and 10% after MB. Only 2 of 13,749 patients (0.015%) experienced both MB and ST during the entire 1-year follow-up period. Conclusions In this worldwide population treated with ≥1 SES, the reported compliance with DAPT was good, and the incidence of ST and MB was low. Stent thrombosis and MB very rarely occurred in the same patient. (The e-SELECT Registry: a Multicenter Post-Market Surveillance; NCT00438919).
Affiliations:
- Allemagne, Australie, Belgique, Brésil, Canada, Corée du Sud, France, Italie, Royaume-Uni, République populaire de Chine, Suisse, États-Unis
- Angleterre, Lombardie, Minnesota, Ohio, Oxfordshire, Île-de-France
- Milan, Oxford, Paris, Pékin
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Stent Thrombosis and Bleeding Complications After Implantation of Sirolimus-Eluting Coronary Stents in an Unselected Worldwide Population: A Report From the e-SELECT (Multi-Center Post-Market Surveillance) Registry</title><author><name sortKey="Urban, Philip" sort="Urban, Philip" uniqKey="Urban P" first="Philip" last="Urban">Philip Urban</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>La Tour Hospital</s1><s2>Geneva</s2><s3>CHE</s3><sZ>1 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>La Tour Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Abizaid, Alexandre" sort="Abizaid, Alexandre" uniqKey="Abizaid A" first="Alexandre" last="Abizaid">Alexandre Abizaid</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Instituto Dante Pazzanese de Cardiologia</s1><s2>São Paolo</s2><s3>BRA</s3><sZ>2 aut.</sZ></inist:fA14><country>Brésil</country><wicri:noRegion>Instituto Dante Pazzanese de Cardiologia</wicri:noRegion></affiliation></author><author><name sortKey="Banning, Adrian" sort="Banning, Adrian" uniqKey="Banning A" first="Adrian" last="Banning">Adrian Banning</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>John Radcliffe Hospital</s1><s2>Oxford</s2><s3>GBR</s3><sZ>3 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Bartorelli, Antonio L" sort="Bartorelli, Antonio L" uniqKey="Bartorelli A" first="Antonio L." last="Bartorelli">Antonio L. Bartorelli</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Centro Cardiologico Monzino, IRCCS, University of Milan</s1><s2>Milan</s2><s3>ITA</s3><sZ>4 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Baux, Ana Cebrian" sort="Baux, Ana Cebrian" uniqKey="Baux A" first="Ana Cebrian" last="Baux">Ana Cebrian Baux</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Cordis Clinical Research Europe</s1><s2>Waterloo</s2><s3>BEL</s3><sZ>5 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>Belgique</country><wicri:noRegion>Cordis Clinical Research Europe</wicri:noRegion></affiliation></author><author><name sortKey="Dzavik, Vladimir" sort="Dzavik, Vladimir" uniqKey="Dzavik V" first="Vladimir" last="Dzavik">Vladimir Dzavik</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Peter Munk Cardiac Centre, University Health Network</s1><s2>Toronto, Ontario</s2><s3>CAN</s3><sZ>6 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Toronto, Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Ellis, Stephen" sort="Ellis, Stephen" uniqKey="Ellis S" first="Stephen" last="Ellis">Stephen Ellis</name><affiliation wicri:level="2"><inist:fA14 i1="07"><s1>Cleveland Clinic Foundation</s1><s2>Cleveland, Ohio</s2><s3>USA</s3><sZ>7 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Gao, Runlin" sort="Gao, Runlin" uniqKey="Gao R" first="Runlin" last="Gao">Runlin Gao</name><affiliation wicri:level="3"><inist:fA14 i1="08"><s1>Cardiovascular Institute and Fu Wai Hospital</s1><s2>Beijing</s2><s3>CHN</s3><sZ>8 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Holmes, David" sort="Holmes, David" uniqKey="Holmes D" first="David" last="Holmes">David Holmes</name><affiliation wicri:level="2"><inist:fA14 i1="09"><s1>Mayo Clinic</s1><s2>Rochester, Minnesota</s2><s3>USA</s3><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Myung Ho Jeong" sort="Myung Ho Jeong" uniqKey="Myung Ho Jeong" last="Myung Ho Jeong">MYUNG HO JEONG</name><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>The Heart Center of Chonnam National University Hospital</s1><s2>Gwangju</s2><s3>KOR</s3><sZ>10 aut.</sZ></inist:fA14><country>Corée du Sud</country><wicri:noRegion>The Heart Center of Chonnam National University Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Legrand, Victor" sort="Legrand, Victor" uniqKey="Legrand V" first="Victor" last="Legrand">Victor Legrand</name><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Centre Hospitalier Universitaire</s1><s2>Liege</s2><s3>BEL</s3><sZ>11 aut.</sZ></inist:fA14><country>Belgique</country><wicri:noRegion>Centre Hospitalier Universitaire</wicri:noRegion></affiliation></author><author><name sortKey="Neumann, Franz Josef" sort="Neumann, Franz Josef" uniqKey="Neumann F" first="Franz-Josef" last="Neumann">Franz-Josef Neumann</name><affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Herz-Zentrum Bad Krozingen</s1><s2>Bad Krozingen</s2><s3>DEU</s3><sZ>12 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Bad Krozingen</wicri:noRegion><wicri:noRegion>Herz-Zentrum Bad Krozingen</wicri:noRegion><wicri:noRegion>Herz-Zentrum Bad Krozingen</wicri:noRegion></affiliation></author><author><name sortKey="Nyakern, Maria" sort="Nyakern, Maria" uniqKey="Nyakern M" first="Maria" last="Nyakern">Maria Nyakern</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Cordis Clinical Research Europe</s1><s2>Waterloo</s2><s3>BEL</s3><sZ>5 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>Belgique</country><wicri:noRegion>Cordis Clinical Research Europe</wicri:noRegion></affiliation></author><author><name sortKey="Spaulding, Christian" sort="Spaulding, Christian" uniqKey="Spaulding C" first="Christian" last="Spaulding">Christian Spaulding</name><affiliation wicri:level="3"><inist:fA14 i1="13"><s1>Department of Cardiology, Cochin Hospital, Assistance Publique Hôpitaux de Paris and INSERM U 970, Paris Descartes University</s1><s2>Paris</s2><s3>FRA</s3><sZ>14 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Worthley, Stephen" sort="Worthley, Stephen" uniqKey="Worthley S" first="Stephen" last="Worthley">Stephen Worthley</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Cardiovascular Investigation Unit, Royal Adelaide Hospital</s1><s2>Adelaide</s2><s3>AUS</s3><sZ>15 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Adelaide</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">11-0202766</idno><date when="2011">2011</date><idno type="stanalyst">PASCAL 11-0202766 INIST</idno><idno type="RBID">Pascal:11-0202766</idno><idno type="wicri:Area/PascalFrancis/Corpus">001E21</idno><idno type="wicri:Area/PascalFrancis/Curation">004119</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">001658</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">001658</idno><idno type="wicri:doubleKey">0735-1097:2011:Urban P:stent:thrombosis:and</idno><idno type="wicri:Area/Main/Merge">006B09</idno><idno type="wicri:Area/Main/Curation">006706</idno><idno type="wicri:Area/Main/Exploration">006706</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Stent Thrombosis and Bleeding Complications After Implantation of Sirolimus-Eluting Coronary Stents in an Unselected Worldwide Population: A Report From the e-SELECT (Multi-Center Post-Market Surveillance) Registry</title><author><name sortKey="Urban, Philip" sort="Urban, Philip" uniqKey="Urban P" first="Philip" last="Urban">Philip Urban</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>La Tour Hospital</s1><s2>Geneva</s2><s3>CHE</s3><sZ>1 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>La Tour Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Abizaid, Alexandre" sort="Abizaid, Alexandre" uniqKey="Abizaid A" first="Alexandre" last="Abizaid">Alexandre Abizaid</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Instituto Dante Pazzanese de Cardiologia</s1><s2>São Paolo</s2><s3>BRA</s3><sZ>2 aut.</sZ></inist:fA14><country>Brésil</country><wicri:noRegion>Instituto Dante Pazzanese de Cardiologia</wicri:noRegion></affiliation></author><author><name sortKey="Banning, Adrian" sort="Banning, Adrian" uniqKey="Banning A" first="Adrian" last="Banning">Adrian Banning</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>John Radcliffe Hospital</s1><s2>Oxford</s2><s3>GBR</s3><sZ>3 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Bartorelli, Antonio L" sort="Bartorelli, Antonio L" uniqKey="Bartorelli A" first="Antonio L." last="Bartorelli">Antonio L. Bartorelli</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Centro Cardiologico Monzino, IRCCS, University of Milan</s1><s2>Milan</s2><s3>ITA</s3><sZ>4 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Baux, Ana Cebrian" sort="Baux, Ana Cebrian" uniqKey="Baux A" first="Ana Cebrian" last="Baux">Ana Cebrian Baux</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Cordis Clinical Research Europe</s1><s2>Waterloo</s2><s3>BEL</s3><sZ>5 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>Belgique</country><wicri:noRegion>Cordis Clinical Research Europe</wicri:noRegion></affiliation></author><author><name sortKey="Dzavik, Vladimir" sort="Dzavik, Vladimir" uniqKey="Dzavik V" first="Vladimir" last="Dzavik">Vladimir Dzavik</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Peter Munk Cardiac Centre, University Health Network</s1><s2>Toronto, Ontario</s2><s3>CAN</s3><sZ>6 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Toronto, Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Ellis, Stephen" sort="Ellis, Stephen" uniqKey="Ellis S" first="Stephen" last="Ellis">Stephen Ellis</name><affiliation wicri:level="2"><inist:fA14 i1="07"><s1>Cleveland Clinic Foundation</s1><s2>Cleveland, Ohio</s2><s3>USA</s3><sZ>7 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Gao, Runlin" sort="Gao, Runlin" uniqKey="Gao R" first="Runlin" last="Gao">Runlin Gao</name><affiliation wicri:level="3"><inist:fA14 i1="08"><s1>Cardiovascular Institute and Fu Wai Hospital</s1><s2>Beijing</s2><s3>CHN</s3><sZ>8 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Holmes, David" sort="Holmes, David" uniqKey="Holmes D" first="David" last="Holmes">David Holmes</name><affiliation wicri:level="2"><inist:fA14 i1="09"><s1>Mayo Clinic</s1><s2>Rochester, Minnesota</s2><s3>USA</s3><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Myung Ho Jeong" sort="Myung Ho Jeong" uniqKey="Myung Ho Jeong" last="Myung Ho Jeong">MYUNG HO JEONG</name><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>The Heart Center of Chonnam National University Hospital</s1><s2>Gwangju</s2><s3>KOR</s3><sZ>10 aut.</sZ></inist:fA14><country>Corée du Sud</country><wicri:noRegion>The Heart Center of Chonnam National University Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Legrand, Victor" sort="Legrand, Victor" uniqKey="Legrand V" first="Victor" last="Legrand">Victor Legrand</name><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Centre Hospitalier Universitaire</s1><s2>Liege</s2><s3>BEL</s3><sZ>11 aut.</sZ></inist:fA14><country>Belgique</country><wicri:noRegion>Centre Hospitalier Universitaire</wicri:noRegion></affiliation></author><author><name sortKey="Neumann, Franz Josef" sort="Neumann, Franz Josef" uniqKey="Neumann F" first="Franz-Josef" last="Neumann">Franz-Josef Neumann</name><affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Herz-Zentrum Bad Krozingen</s1><s2>Bad Krozingen</s2><s3>DEU</s3><sZ>12 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Bad Krozingen</wicri:noRegion><wicri:noRegion>Herz-Zentrum Bad Krozingen</wicri:noRegion><wicri:noRegion>Herz-Zentrum Bad Krozingen</wicri:noRegion></affiliation></author><author><name sortKey="Nyakern, Maria" sort="Nyakern, Maria" uniqKey="Nyakern M" first="Maria" last="Nyakern">Maria Nyakern</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Cordis Clinical Research Europe</s1><s2>Waterloo</s2><s3>BEL</s3><sZ>5 aut.</sZ><sZ>13 aut.</sZ></inist:fA14><country>Belgique</country><wicri:noRegion>Cordis Clinical Research Europe</wicri:noRegion></affiliation></author><author><name sortKey="Spaulding, Christian" sort="Spaulding, Christian" uniqKey="Spaulding C" first="Christian" last="Spaulding">Christian Spaulding</name><affiliation wicri:level="3"><inist:fA14 i1="13"><s1>Department of Cardiology, Cochin Hospital, Assistance Publique Hôpitaux de Paris and INSERM U 970, Paris Descartes University</s1><s2>Paris</s2><s3>FRA</s3><sZ>14 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Worthley, Stephen" sort="Worthley, Stephen" uniqKey="Worthley S" first="Stephen" last="Worthley">Stephen Worthley</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Cardiovascular Investigation Unit, Royal Adelaide Hospital</s1><s2>Adelaide</s2><s3>AUS</s3><sZ>15 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Adelaide</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Journal of the American College of Cardiology</title><title level="j" type="abbreviated">J. Am. Coll. Cardiol.</title><idno type="ISSN">0735-1097</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Journal of the American College of Cardiology</title><title level="j" type="abbreviated">J. Am. Coll. Cardiol.</title><idno type="ISSN">0735-1097</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antibacterial agent</term><term>Antibiotic</term><term>Cardiology</term><term>Center</term><term>Circulatory system</term><term>Complication</term><term>Coronary artery</term><term>Coronary heart disease</term><term>Drug eluting stent</term><term>Endoprosthesis</term><term>Hemorrhage</term><term>Immunosuppressive agent</term><term>Implantation</term><term>Instrumentation therapy</term><term>Markets</term><term>Population</term><term>Sirolimus</term><term>Surveillance</term><term>Thrombosis</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Thrombose</term><term>Hémorragie</term><term>Cardiopathie coronaire</term><term>Stent à élution médicamenteuse</term><term>Endoprothèse</term><term>Complication</term><term>Implantation</term><term>Sirolimus</term><term>Immunodépresseur</term><term>Artère coronaire</term><term>Population</term><term>Centre</term><term>Marché</term><term>Surveillance</term><term>Appareil circulatoire</term><term>Cardiologie</term><term>Traitement instrumental</term><term>Antibactérien</term><term>Antibiotique</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Région Centre</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Marché</term><term>Antibiotique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objectives The aim of this study was to ascertain the 1-year incidence of stent thrombosis (ST) and major bleeding (MB) in a large, unselected population treated with sirolimus-eluting stents (SES). Background Stent thrombosis and MB are major potential complications of drug-eluting stent implantation. Their relative incidence and predisposing factors among large populations treated worldwide are unclear. Methods The SES were implanted in 15,147 patients who were entered in a multinational registry. We analyzed the incidence of: 1) definite and probable ST as defined by the Academic Research Consortium; and 2) MB, with the STEEPLE (Safety and efficacy of Enoxaparin in PCI) definition, together with their relation to dual antiplatelet therapy (DAPT) and to 1-year clinical outcomes. Results The mean age of the sample was 62 ± 11 years, 30.4% were diabetic, 10% had a Charlson comorbidity index ≥3, and 44% presented with acute coronary syndrome or myocardial infarction. At 1 year, the reported compli- ance with DAPT as recommended by the European Society of Cardiology guidelines was 86.3%. Adverse event rates were: ST 1.0%, MB 1.0%, mortality 1.7%, myocardial infarction 1.9%, and target lesion revascularization 2.3%. Multivariate analysis identified 9 correlates of ST and 4 correlates of MB. Advanced age and a high Charlson index were associated with an increased risk of both ST and MB. After ST, the 7-day and 1-year all-cause mortality was 30% and 35%, respectively, versus 1.5% and 10% after MB. Only 2 of 13,749 patients (0.015%) experienced both MB and ST during the entire 1-year follow-up period. Conclusions In this worldwide population treated with ≥1 SES, the reported compliance with DAPT was good, and the incidence of ST and MB was low. Stent thrombosis and MB very rarely occurred in the same patient. (The e-SELECT Registry: a Multicenter Post-Market Surveillance; NCT00438919).</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Belgique</li><li>Brésil</li><li>Canada</li><li>Corée du Sud</li><li>France</li><li>Italie</li><li>Royaume-Uni</li><li>République populaire de Chine</li><li>Suisse</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Lombardie</li><li>Minnesota</li><li>Ohio</li><li>Oxfordshire</li><li>Île-de-France</li></region><settlement><li>Milan</li><li>Oxford</li><li>Paris</li><li>Pékin</li></settlement></list><tree><country name="Suisse"><noRegion><name sortKey="Urban, Philip" sort="Urban, Philip" uniqKey="Urban P" first="Philip" last="Urban">Philip Urban</name></noRegion></country><country name="Brésil"><noRegion><name sortKey="Abizaid, Alexandre" sort="Abizaid, Alexandre" uniqKey="Abizaid A" first="Alexandre" last="Abizaid">Alexandre Abizaid</name></noRegion></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Banning, Adrian" sort="Banning, Adrian" uniqKey="Banning A" first="Adrian" last="Banning">Adrian Banning</name></region></country><country name="Italie"><region name="Lombardie"><name sortKey="Bartorelli, Antonio L" sort="Bartorelli, Antonio L" uniqKey="Bartorelli A" first="Antonio L." last="Bartorelli">Antonio L. Bartorelli</name></region></country><country name="Belgique"><noRegion><name sortKey="Baux, Ana Cebrian" sort="Baux, Ana Cebrian" uniqKey="Baux A" first="Ana Cebrian" last="Baux">Ana Cebrian Baux</name></noRegion><name sortKey="Legrand, Victor" sort="Legrand, Victor" uniqKey="Legrand V" first="Victor" last="Legrand">Victor Legrand</name><name sortKey="Nyakern, Maria" sort="Nyakern, Maria" uniqKey="Nyakern M" first="Maria" last="Nyakern">Maria Nyakern</name></country><country name="Canada"><noRegion><name sortKey="Dzavik, Vladimir" sort="Dzavik, Vladimir" uniqKey="Dzavik V" first="Vladimir" last="Dzavik">Vladimir Dzavik</name></noRegion></country><country name="États-Unis"><region name="Ohio"><name sortKey="Ellis, Stephen" sort="Ellis, Stephen" uniqKey="Ellis S" first="Stephen" last="Ellis">Stephen Ellis</name></region><name sortKey="Holmes, David" sort="Holmes, David" uniqKey="Holmes D" first="David" last="Holmes">David Holmes</name></country><country name="République populaire de Chine"><noRegion><name sortKey="Gao, Runlin" sort="Gao, Runlin" uniqKey="Gao R" first="Runlin" last="Gao">Runlin Gao</name></noRegion></country><country name="Corée du Sud"><noRegion><name sortKey="Myung Ho Jeong" sort="Myung Ho Jeong" uniqKey="Myung Ho Jeong" last="Myung Ho Jeong">MYUNG HO JEONG</name></noRegion></country><country name="Allemagne"><noRegion><name sortKey="Neumann, Franz Josef" sort="Neumann, Franz Josef" uniqKey="Neumann F" first="Franz-Josef" last="Neumann">Franz-Josef Neumann</name></noRegion></country><country name="France"><region name="Île-de-France"><name sortKey="Spaulding, Christian" sort="Spaulding, Christian" uniqKey="Spaulding C" first="Christian" last="Spaulding">Christian Spaulding</name></region></country><country name="Australie"><noRegion><name sortKey="Worthley, Stephen" sort="Worthley, Stephen" uniqKey="Worthley S" first="Stephen" last="Worthley">Stephen Worthley</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= Stent Thrombosis and Bleeding Complications After Implantation of Sirolimus-Eluting Coronary Stents in an Unselected Worldwide Population: A Report From the e-SELECT (Multi-Center Post-Market Surveillance) Registry
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